Sunday, August 17, 2025

Polaris of Enlightenment

Neuralink’s first patient uses mind to move cursor

Published 21 March 2024
– By Editorial Staff
After what he calls a "freak diving accident", Noland Arbaugh, 29, has no feeling or movement from the shoulders down.
3 minute read

Elon Musk’s biotech venture Neuralink has unveiled its first human trial patient: Noland Arbaugh, 29. After receiving a special brain implant, Arbaugh, who has been paralysed from the shoulders down for eight years, is now able to move a cursor on a computer screen using only his mind.

– It’s like using ‘The Force’ on the cursor, says Arbaugh.

In alignment with Neuralink’s ambitious goal to “create a generalized brain interface to restore autonomy to individuals with unmet medical needs and to unlock human potential for the future”, Arbaugh showcased his newfound ability to play online chess and the strategy game Civilization VI using his mind during a livestream on Twitter/X.

– I’m so freakin’ lucky to be a part of this. I just can’t even describe how cool it is to be able to do this.

Founded in 2016, Neuralink’s road to human trials has been lengthy. Their original plan to begin human trials in 2020 was delayed until May last year, when the FDA finally gave Neuralink the go-ahead to begin human trials. Until then, the company had been using monkeys in its tests, which had caused some controversy.

Invasive robot surgery

To create a brain-computer interface, a two-part device called the N1 implant is used. The first part, which sits outside the skull, contains a battery, a bluetooth antenna and the tiny computer that controls the implant. The second part, the “neural lace”, consists of “1,024 electrodes distributed over 64 threads”, which perform the essential service of detecting neural signals or “spikes” in the brain. The neural lace has to be implanted in the brain using a special surgical robot, also developed by Neuralink.

– You open a piece of skull. You remove a coin-sized piece of skull. And then the robot inserts the electrodes. Then the device replaces the portion of skull that was removed. And we basically close that up with actually super glue, which is how a lot of wounds are closed. And then you can just walk around right afterwards. It’s pretty cool, says Elon Musk himself about the surgical process.

A Neuralink employee holding implant prototypes. Photo: Neuralink.

– The surgery was super easy, I literally was released from the hospital a day later. I have no cognitive impairments, none that were caused by the surgery anyway, Arbaugh jokes about the surgical process.

“Changed my life”

Asked if he had any final remarks to close the live stream, Arbaugh said:

– It’s not perfect. I would say that we have run into some issues. I don’t want people to think this is the end of the journey, there’s still a lot of work to be done. But it has already changed my life and I think that people who are thinking about applying for the human trials or are thinking about finding some way to help out with this.

– The reason I got into this was because I just wanted to help, I wanted to be part of something that I feel like is going to change the world.

Commenting on the live stream, Musk himself took the opportunity to explain part of Neuralink’s wider ambition to help the disabled.

“Long-term, it is possible to shunt the signals from the brain motor cortex past the damaged part of the spine to enable people to walk again and use their arms normally”, he writes.

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Comet from another solar system approaches Earth

Published 12 August 2025
– By Editorial Staff
The comet has not yet developed a tail, but has a "teardrop-shaped cocoon of dust".
2 minute read

A rare comet is approaching our solar system – but it will pass at a safe distance. In September, it may become visible to amateur telescopes.

The comet was discovered on July 1 this year by the Atlas telescope in Chile and was given the name 3I/Atlas. It is the third interstellar object ever observed passing through our solar system – hence the number three in its name. The two previous objects are 1I/’Oumuamua, discovered in 2017, and 2I/Borisov, discovered in 2019. The letter “I” stands for interstellar.

When NASA photographed the comet with the Hubble telescope on July 21, it was located approximately 447 million kilometers from Earth. Although it had not yet developed a typical tail, observers could see that the process was underway.

“Hubble shows that the comet has a teardrop-shaped cocoon of dust coming off its solid, icy nucleus. Because Hubble was tracking the comet moving along a hyperbolic trajectory, the stationary background stars are streaked in the exposure”, writes NASA.

Unknown origin

The comet is currently traveling through space at a speed of approximately 210,000 kilometers per hour. It will pass closer to Mars than to Earth, but at a safe distance from both planets and therefore poses no threat. Astronomers initially estimated that the icy nucleus was several kilometers in diameter, but Hubble’s observations have refined the estimate to at most 5.6 kilometers – possibly as small as 320 meters.

3I/Atlas is expected to become visible even to amateur telescopes in September, according to CBS News. It will pass closest to the sun in October, but will not be visible from Earth at that time. In early December, it is expected to reappear on the other side of the sun, enabling new observations.

Which solar system the comet originates from is still unknown. As it approaches the sun, it will melt more and release gases that telescopes can analyze – gases that may provide clues about the comet’s origin.

Women’s pelvises becoming narrower

Published 4 August 2025
– By Editorial Staff
Midwives and cesarean sections may have played a role in evolutionary change, researchers suggest.
3 minute read

Over the past century, women’s pelvises have shrunk, according to a study that examined women in three different countries. Researchers see possible explanations in evolutionary development, where increased use of midwives and cesarean sections may have played a role.

In the study, researchers examined a total of 8,866 women in Australia, Poland and Mexico between 1880 and 1980. Researchers from the University of Łódź in Poland and the University of Adelaide in Australia looked at women’s bodies and how these have changed during that time period.

During this century-long period, they found that women’s pelvises in all three countries had shrunk by an average of 4.5 centimeters. At the same time, women’s height had increased by an average of 10 centimeters. Shoulder width had not changed noticeably.

The study is still a so-called preprint, which means it has not yet been reviewed by other researchers, but it nevertheless generates great interest.

The dataset is fantastic, says researcher Lia Betti at University College London to The New Scientist.

More difficult deliveries

With narrower pelvises, vaginal deliveries can become more complicated, while it can also reduce women’s risk of pelvic floor problems after delivery. In all three countries, approximately 40 percent of all births are assisted, meaning cesarean sections, forceps or vacuum extraction are used during deliveries.

The researchers believe that a reduced pelvis may partly be an evolutionary development since pelvic width is hereditary. Previously, birth canals that were too narrow could be life-threatening for both mother and child. But today, many difficult deliveries are resolved surgically or in other ways. In this way, genetic variants are passed on that previously could have led to fatal complications for mother and child. It is also more advantageous for humans to have smaller pelvises to more easily walk on two legs, but at the same time it becomes a dilemma since humans give birth to children with very large heads compared to other species.

Researcher Philipp Mitteroecker at the University of Vienna in Austria has studied women’s pelvises in a 2024 study, which also points out that narrower pelvises for women have more advantages than just being able to walk more easily on two legs. If the pelvis is wider, the load becomes greater and the pressure on the pelvic floor increases. The risk of urinary incontinence and what is called prolapse therefore becomes greater.

The unique midwife

Mitteroecker also points to the development of midwives, that is, the unique aspect that women for hundreds of thousands of years have received help from others during delivery. This may also have contributed to weakening the natural evolutionary pressure to give women wider pelvises.

C-section is, in a way, an extreme form of that, Mitteroecker tells The New Scientist.

At the same time, Betti is skeptical that assisted deliveries and especially cesarean sections – as well as heredity and evolution – alone can explain the increasing narrowing of women’s pelvises. She points out that humans have also become significantly taller during the same period. But this increased height is probably largely due to better nutrition – not genetic changes.

When nutrition is scarce, our developing bodies tend to allocate more nutrients to certain organs, including the brain, at the expense of others. But now we have ample nutrition, so our bodies may have reallocated nutrients. So we end up with different body proportions, she says.

Researchers: Gut bacteria may protect against PFAS

Published 4 August 2025
– By Editorial Staff
2 minute read

Certain gut bacteria can absorb PFAS substances, according to new research from Cambridge University. An increase in these bacteria could contribute to better protection against the harmful effects of so-called forever chemicals.

In the study, which was published in Nature Microbiology, researchers identified a family of bacterial species that can absorb various PFAS molecules. These bacteria are naturally found in the human gut flora.

The researchers then added nine of these human bacteria to mice to “humanize” their microbiome and fed them food containing PFAS substances. They could then observe that the bacteria accumulated the chemicals, which were subsequently excreted in feces.

Furthermore, the researchers discovered that when the mice were exposed to increasing levels of PFAS, the bacteria worked harder and removed a consistent proportion of the toxic substances. Within minutes of exposure, the bacteria absorbed between 25 and 74 percent of PFAS.

“Slow poison”

PFAS are now found virtually everywhere – in everyday products, drinking water, food, and even in human blood. They are extremely difficult to break down, which has earned them the nickname “forever chemicals,” and can cause damage to both the environment and human health.

We’re all being exposed to PFAS through our water and food – these chemicals are so widespread that they’re in all of us., says researcher Dr Anna Lindell at Cambridge University, first author of the study, in a press release and continues:

PFAS were once considered safe, but it’s now clear that they’re not. It’s taken a long time for PFAS to become noticed because at low levels they’re not acutely toxic. But they’re like a slow poison.

Opens possibilities

The study’s results are promising and show for the first time that gut bacteria can help remove PFAS from the body. However, it has not yet been tested on humans, the researchers emphasize.

The goal is now to develop probiotic supplements that increase the amount of these beneficial bacteria in the gut and thereby protect against PFAS effects. The researchers point out that despite the documented health risks, very little is still being done to actively remove PFAS from the body.

The reality is that PFAS are already in the environment and in our bodies, and we need to try and mitigate their impact on our health now. We haven’t found a way to destroy PFAS, but our findings open the possibility of developing ways to get them out of our bodies where they do the most harm, says Dr Indra Roux, co-author of the study.

Researchers’ new IVF method: Children born with DNA from three people

Published 20 July 2025
– By Editorial Staff
Archive image.
2 minute read

Eight children are reported to have been born in the United Kingdom with DNA from a mother and a father – and an additional person. The method has been justified as preventing the risk of inheriting life-threatening genetic diseases from parents.

The intervention technique is described in British media as groundbreaking and became possible after the UK changed legislation in the area in 2015. The UK’s fertility authority granted the first license in 2017 to a clinic at Newcastle University, where doctors were the very first to use the technique that reportedly aims to help women with mitochondrial diseases give birth to healthy children through artificial insemination.

Four boys and four girls, including a pair of identical twins, have been born through the method technically called mitochondrial donation therapy. The children currently show no signs of the mitochondrial diseases they risked inheriting. Another pregnancy is still ongoing.

Third person’s genes are passed on

As parents, all we ever wanted was to give our child a healthy start in life. After years of uncertainty this treatment gave us hope – and then it gave us our baby … we’re overwhelmed with gratitude. Science gave us a chance“, says the mother of one of the girls according to the British liberal newspaper The Guardian.

The mitochondria affected by the treatment constitute 0.02 percent of human total DNA, which is why the researchers behind the technique do not fully embrace the description of the technique as giving rise to “three parents”. At the same time, mitochondria have their own genetic code and girls born with the help of this technique – and who carry the healthy third person’s/donor’s mitochondria – will pass on these genes to their potential children as well.

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