Saturday, April 19, 2025

Polaris of Enlightenment

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Lower testicular volume in overweight boys

Published 22 May 2023
– By Editorial Staff
Normal weight boys statistically had a 1.5 times larger testicular volume than overweight ones.

Boys who are overweight or have insulin resistance are more likely to have smaller testicular volume, which can negatively affect their fertility in adulthood. The researchers suggest that losing weight could “represent a prevention strategy for maintaining testicular function later in life”.

Infertility is becoming increasingly common and in the Western world around 15 to 20 percent of couples experience infertility problems at some point in their reproductive lives. Epidemiologist Shanna Swan has done a lot of research on the subject, with her previous studies finding that sperm production in Western men decreased by 59% between 1973 and 2011.

Swan and other researchers point out that the problems may be due to a number of factors such as hazardous chemicals and unhealthy lifestyles. With the decline in sperm production in men, the incidence of obesity has also increased, especially in children.

A new study from Oxford University, published in the European Journal of Endocrinology, looked at testicular volume in 268 children and adolescents. The researchers collected data on age, body mass index (BMI), insulin resistance and testicular volume in children aged nine years and under (pre-pubertal), nine to 14 years (peri-pubertal) and 14 to 16 years (post-pubertal).

Although the prevalence of childhood obesity is increasing worldwide, the impact of obesity and associated metabolic disorders on testicular growth is not well known, Rossella Cannarella, one of the authors of the study, said in a press release.

The study found that normal-weight boys aged 9 to 14 years had 1.5 times the testicular volume of those who were overweight or obese. In the other age groups, no difference in BMI was found.

In children aged under nine and over 14, those with normal insulin levels were found to have 1.5 to 2 times the testicular volume of boys with hyperinsulinism, a condition often associated with type 2 diabetes. Boys aged 14 to 16 who had insulin resistance also had smaller testicular volume.

The researchers believe that because smaller testicular volume is associated with poorer sperm production in adulthood, weight loss may help children avoid infertility in the future.

– In this study, we found that being overweight or obese was associated with a lower peri-pubertal testicular volume, Cannarella notes. Therefore, we speculate that more careful control of body weight in childhood could represent a prevention strategy for maintaining testicular function later in life.

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Painkillers linked to increased risk propensity

Published today 15:43
– By Editorial Staff
If large groups have an impaired perception of risk, this can have significant societal consequences.

Paracetamol can affect how we perceive risk, according to a US study. Students given painkillers before experiments were found to take greater risks than those given a placebo – something the researchers say may also have societal implications.

Paracetamol is an over-the-counter medication commonly taken for pain and fever and is available in the form of several different brands such as Alvedon, Orifarm and Apofri.

In the study, which was published in Social Cognitive and Affective Neuroscience in 2020, participants were asked to perform various experiments and then assessed based on their risk-taking. Over 500 university students took part in the experiments, with half of the group receiving a single dose of 1000 milligrams of acetaminophen before the experiments, and the rest receiving a placebo.

In one of the experiments, participants had to inflate balloons via a computer game, with each individual pump providing pretend money. The point was not to blow up the balloon with too much air as all the money earned would be lost. The results showed that the students taking paracetamol engaged in significantly more risk-taking during the exercise, compared to the more cautious placebo group.

Overall, those taking paracetamol inflated, and burst, their balloons more than the control group.

“Less negative emotions”

Researcher Baldwin Way from Ohio State University, who is behind the study, believes that this may have to do with the fact that paracetamol has a certain anxiolytic effect.

If you’re risk-averse, you may pump a few times and then decide to cash out because you don’t want the balloon to burst and lose your money, Way says, adding:

But for those who are on acetaminophen, as the balloon gets bigger, we believe they have less anxiety and less negative emotion about how big the balloon is getting and the possibility of it bursting.

The balloon experiment was repeated twice, with similar results. Furthermore, during the experiments, participants were asked to complete questionnaires in which they had to assess risk levels around hypothetical scenarios. For example, betting a day’s income on a sporting event, bungee jumping off a high bridge or driving a car without a seatbelt.

“Significant effects on society”

Those who had taken paracetamol were clearly more comfortable with, for example, the idea of driving without a seatbelt compared to the placebo group.

Way says the study suggests that the substance “seems to make people feel less negative emotion when they consider risky activities”, which he says could have implications for society.

With nearly 25 per cent of the population in the US taking acetaminophen each week, reduced risk perceptions and increased risk-taking could have important effects on society, he says.

Comment: An entire world was injected – but the silence about the long-term side effects is total

The criticized covid vaccinations

Early warnings about the long-term risks of experimental mRNA vaccines were dismissed as conspiracy theorists and quacks. In hindsight, most evidence suggests that their fears were justified and new findings indicate that the vaccines can cause long-term changes in the genetic structure of the body.

Published yesterday 11:23
– By Jenny Piper
A German study shows that the COVID-19 vaccine can affect the genetic structure of the body, triggering inflammatory reactions, autoimmune conditions and in some cases cancer.
{ $opinionDisclaimer }

Even at the beginning of the mass vaccination hysteria, I often wrote about the risks of taking the mRNA vaccine shots because the long-term side effects of this fast-acting so-called vaccine are unknown and will only become apparent in a few years.

Whistleblowers from within the pharmaceutical industry had also flagged this very aspect early on – that it is designed to seek out possible weaknesses in people’s immune systems, where it accelerates the development of cancer, autoimmune diseases and cardiovascular diseases. This was of course dismissed as quackery and conspiracy theories, which is why the vast majority of the population rolled up their sleeves at least twice.

Now, a new peer-reviewed study from Germany on mRNA-based Covid-19 vaccines shows that they can cause long-term changes in the body’s genetic structure – changes that in turn can trigger inflammatory reactions, autoimmune conditions and, in some cases, cancer.

19 researchers at leading German institutions conducted the study, which was published in Molecular Systems Biology at the end of March. It shows a possible link between mRNA vaccines and epigenetic changes in immune cells, specifically linked to a protein called histone 3 lysine 27 acetylation (H3K27ac), a protein that has been associated with leukemia and brain tumors.

Histones act as “coils” around which the DNA strand is wound, helping to give DNA its three-dimensional structure. Changes in these proteins affect how genes are expressed. The looser the histones are, the more actively the DNA is transcribed, which in some cases can stimulate tumor growth.

The researchers analyzed how the chromosomes of macrophages (a type of white blood cell) are affected by mRNA vaccination. The results showed persistent epigenetic changes in these cells, which could explain some post-vaccination inflammatory diseases.

Histone modifications – where the structure of DNA is altered without changing the DNA code itself – can play an important role in how genes are expressed. In this case, the researchers found a change in H3K27ac that persisted for months after vaccination, raising concerns about possible long-term effects on the immune system.

According to the researchers, changes in H3K27ac can be linked to several cancers, including gliomas (brain tumors) and leukemia. Other studies, including those from China and Poland, have also linked this particular type of histone modification to cancer.

Several scientists and experts have commented on the study.

Alex Berenson, an independent journalist, says the results show how mRNA vaccines can affect chromosomes in a way that is associated with brain tumors and leukemia.

Nicolas Hulscher, an epidemiologist, says the study adds to a growing body of evidence that mRNA vaccines can disrupt the balance of the immune system and lead to chronic inflammatory conditions.

Jessica Rose, Ph.D., immunologist and biochemist, points out that it is already known that repeated injections cause immunological changes and that these changes can reach stem cells and affect the long-term functioning of the immune system.

Other studies have shown that the levels of synthetic DNA in some vaccine doses (from Pfizer and Moderna) have been well above permissible limits – in some cases up to 470 times higher than regulatory guidelines allow.

The fact that so-called turbo cancer has risen sharply in recent years is hardly a coincidence. Unfortunately, I think we have only seen the beginning of this – and the Swedish establishment has put a lid on the whole thing.

 

Jenny Piper

All Jenny Piper's articles can be found on her blog.

Researchers create unique brain map using mouse and movie clips

Published 15 April 2025
– By Editorial Staff
The researchers believe that the technology developed could be useful for identifying disorders in the brain.

Using a mouse to watch various movie clips, including The Matrix, scientists have created the largest ever functional 3D map of part of a mammalian brain. The high-resolution map contains more than 200 000 brain cells.

Thoughts, emotions, speech and movements are controlled by neurons in the brain that send signals via axons, dendrites and synapses. But how networks of neurons interact – and how disruptions in these connections can contribute to diseases such as Alzheimer’s or autism – is not yet fully understood.

– You can make a thousand hypotheses about how brain cells might do their job, but you can’t test those hypotheses unless you know perhaps the most fundamental thing – how are those cells wired together, Clay Reid, a researcher at the Allen Institute, tells CBC.

A new project, presented in a total of eight studies by a global team of more than 150 scientists, aims to take brain research a step further by mapping parts of a mouse brain. For two hours, the mouse was shown various clips from movies, including The Matrix, and then researchers were able to map cells in one cubic millimeter of the mouse’s brain tissue, creating a high-resolution 3D map. It contains over 200 000 brain cells, of which about 82 000 are neurons.

The previous most detailed map of a human brain contains 16 000 neurons.

Like looking at the “stars at night”

The new map also captures the activity of tens of thousands of neurons that fire signals and interact with each other to process visual information. The results “are really stunningly beautiful”, says Forrest Collman, a neuroscientist at the Allen Institute, who co-authored the study.

– Looking at it really gives you an awe about the sense of complexity in the brain that is very much akin to looking up at the stars at night, he tells Nature.

The researchers call the project a new fundamental step in brain research and believe that the technique developed could be useful for identifying disorders in the brain. The next step is to map an entire mouse brain.

The technologies developed by this project will give us our first chance to really identify some kind of abnormal pattern of connectivity that gives rise to a disorder, says Sebastian Seung, a Princeton neuroscientist and computer scientist, one of the study’s lead researchers.

Study: Deaths after covid vaccine were in most cases due to the shot

The criticized covid vaccinations

Published 12 April 2025
– By Editorial Staff
Cardiologist Peter McCullough is one of the researchers behind the study.

In a new study, doctors infer covid vaccine as a direct or contributing cause in three out of four cases of 325 autopsies reviewed where individuals took the injections before death.

The researchers reviewed a total of 44 scientific articles with a total of 325 autopsy cases found of people who died after being injected with COVID-19 vaccine. To find the articles, search terms such as “COVID-19 Vaccine”, “SARS-CoV-2 Vaccine”, “COVID Vaccination”, “Post-mortem” and “Autopsy” were used.

In each case, three independent doctors reviewed the autopsy results to assess whether the COVID vaccine could be the direct cause or a contributing cause of death.

Among others, former cardiologist Peter McCullough is one of the researchers behind the study. McCullough has been a very strong critic of the covid policy including the mass vaccination campaign, and strongly urged, among other things, that people under the age of 50 and those who had the infection did not need to inject themselves with the covid vaccines.

Myocarditis and sudden cardiac death

The study, published in the peer-reviewed journal Public Health Policy and the Law, shows that in 74% of cases, at least two out of three physicians considered the COVID-19 vaccination to be a direct or contributing cause of death.

The most common causes of death were sudden cardiac death, pulmonary embolism, myocardial infarction, VITT (vaccine-induced thrombosis), myocarditis, inflammatory syndrome and cerebral hemorrhage. Most deaths studied occurred within a week of vaccination.

Commenting on the study, Swedish physician Nils Littorin says the results are striking.

 

Translation of above tweet: “This is BIG! New medical study of autopsied deaths after COVID-19 vaccine shows that 74% of 326 cases were caused by the vaccine.
The heart and vascular system were the most common organ systems to be injured, followed by hematological and respiratory.” 

Call for in-depth studies

According to the authors, the patterns revealed by the study suggest a causal link between COVID-19 vaccination and increased mortality, while calling for much more extensive and in-depth studies in this area.

Further urgent investigation is required for the purpose of clarifying our findings”, the researchers write.

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