Just a few puffs of an e-cigarette, or vape, containing nicotine can trigger inflammation in the lungs, according to research from Uppsala University in Sweden.
The researchers, who received funding from the Swedish Heart-Lung Foundation, tested 22 healthy individuals on two different occasions. The participants then smoked e-cigarettes both with and without nicotine for half an hour each.
When the researchers analyzed the blood samples, they found that participants exposed to nicotine-containing e-cigarettes showed elevated levels of inflammatory markers in their blood. According to the researchers, this could mean that just a few inhalations are enough to trigger an inflammatory reaction in lung tissue.
— The results are alarming, as they clearly show that e-cigarettes with nicotine are not a harmless alternative to cigarettes. We have long worked to spread scientifically-based knowledge about nicotine’s health effects, and this research strengthens our conviction that tobacco and new nicotine products should be treated equally under the law, says Kristina Sparreljung, Secretary General of the Swedish Heart-Lung Foundation, in a press release.
For the first time, researchers have been able to demonstrate a direct link between inhaled nicotine and specific inflammation markers in the blood that are connected to the lungs. The researchers believe the absorption rate is particularly concerning, as the body absorbs nicotine faster than with nicotine patches, for example.
— Our results are in line with previous studies where nicotine from e-cigarettes has been shown to affect blood vessels by increasing levels of vascular damage markers in the blood. It’s remarkable that even single occasions can produce biological effects. In the long term, this could contribute to the development of both lung diseases and cardiovascular disease, says Fariborz Mobarrez, lecturer and researcher at the Department of Medical Sciences at Uppsala University.
