Friday, March 21, 2025

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Broccoli may reduce the risk of stroke

Published 4 April 2024
– By Editorial Staff
Broccoli may also lower blood sugar and reduce the risk of cancer, according to previous studies.

Broccoli may contain compounds that both prevent and treat stroke, according to Australian research. Scientists believe a new treatment could be available within five years.

Stroke is often caused by the formation of a harmful blood clot in the brain, also known as acute ischemic stroke. The treatment commonly used for this type of stroke is a type of clot-busting drug (r-tPA), which is also designed to help slow the progression of brain damage.

– Unfortunately it is only successful in 20 per cent of cases, Dr. Xuyu (Johnny) Liu of the Heart Research Institute (HRI) in Australia said in a press release.

In the preclinical study, researchers spent three years looking at 23 different compounds found naturally in plants to see which ones would bind to the human compounds. And the compound that was found to work was sulforaphane.

– We are very excited at having isolated a natural compound that may have huge beneficial effects. Our studies will keep exploring how highly purified compounds from vegetables may have beneficial effects in disease processes, says Dr. Liu.

Stroke prevention?

Sulforaphane was able to partially prevent platelets from clumping together. It also prevented blood clots from forming under conditions similar to those found in our arteries. In experiments on mice, the researchers combined sulforaphane with r-tPA, the clot-busting drug, and found that the success rate was up to 60% higher than without the broccoli compound.

– Excitingly, this naturally occurring compound does not cause any signs of bleeding, which is a common side effect associated with blood-thinning agents tested in stroke treatment, says the researcher.

There is also evidence that the broccoli compound could prevent strokes, and Dr. Liu believes it could be used in the future.

– This means we could see paramedics treating ischaemic stroke patients with a broccoli-based medication as well as tPA on the way to hospital, he says.

Nature’s gifts

Broccoli is already known to be rich in vitamins, minerals and antioxidants. Previous studies have also shown that the vegetable, specifically the compound sulforaphane, can lower blood sugar and reduce the risk of cancer. The carotenoids found in broccoli are also thought to reduce the risk of heart disease and boost the immune system.

As sulforaphane moves into clinical trials, it is believed that a new preventive and anticoagulant treatment for stroke could be available in as little as five years.

– We want to understand how nature is giving us gifts to improve our health, says Dr. Liu.

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Sweden to abolish burnout diagnosis under new WHO guidelines

Published 19 March 2025
– By Editorial Staff
The diagnostic criteria have long been criticized for being too broad and vague, leaving much room for interpretation by individual doctors.

Fatigue syndrome will be removed as a diagnosis by 2028, following new guidelines from the World Health Organization (WHO).

Sweden is currently the only country that has fatigue syndrome, also known as burnout, as a recognized diagnosis. The number of stress-related sick leaves is increasing and every year around 20,000 Swedes are taken ill with the diagnosis.

However, as of 2028, the diagnosis will disappear completely from Sweden, reports Psykologitidningen. The background to the decision is that the World Health Organization (WHO) is updating the international diagnosis system and no longer wants to see national diagnoses. In other words, it is not the National Board of Health and Welfare’s decision, but the new guidelines that form the basis for the removal.

Psychologist Elin Lindsäter, one of Sweden’s leading researchers in the field, basically welcomes the change and believes it can benefit patients, as the diagnosis has been broad and vague and used in different ways around the country. At the same time, she worries that the resulting void could lead to rapid decisions and differences between regions. Lindsäter has been in contact with the Minister for Social Affairs, Jakob Forssmed, where she has pointed out the need for national coordination.

– A government commission to investigate the situation seems to be underway, she told the paper.

“Can only get better”

At the same time, she understands that the change may cause concern among patients, who have already pointed out that it can be difficult to get the right care.

– This change puts the clinical picture on the table and forces us to act and think differently. I assume that things can only get better, but initially there may be legitimate concerns for many, with a risk of falling through the cracks.

Magdalena Fresk, Head of the Classifications and Terminology Unit at the National Board of Health and Welfare, says that the previous diagnosis system was many years old and that this is “a long-awaited, medically updated version”. This year they will be working on the translation for the new WHO guidelines.

We have a number of issues that we know we will need to work on to ensure that there are no problems for patients and that it works as well as possible in the future, she told the Bonnier newspaper DN.

Mental health crisis deepens in Swedish schools

Welfare collapse

Published 7 March 2025
– By Editorial Staff

Mental health problems among young Swedes have skyrocketed in recent decades, with the worst performers being those who fail to meet school targets.

A comprehensive study shows that there are clear links between psychiatric diagnoses such as anxiety and depression and poor school performance.

Researchers at Umeå University have followed over three million students between 1990 and 2018 and conclude that the results show that “school performance and mental illness have become increasingly interlinked”.

Psychiatric diagnoses have increased across the youth population, but the trend has been most dramatic among low-achieving students. Mortality from suicide and substance abuse has also increased in this group, while it has remained stable for other youth”, the university writes.

– The increase applies both in the short and long term. We study students when they are in grade 9, but also follow them for several years after they leave primary school. The increase in ill-health is evident even into their 20s, explains Associate Professor Björn Högberg, who participated in the study.

It is seen that mental illness among young people has increased since the 1990s and that Swedish schools have undergone several reforms and changes during this period. These changes have led to an increasing number of students failing to enter or complete their upper secondary education.

Increased risk of suicide

By following all students who completed grade 9 in Sweden between 1990 and 2018, we can see how the correlation between school failure and psychiatric diagnoses has become stronger over time.

– As far as we know, no similar studies have been conducted in any other country, so we do not know if this trend is unique to Sweden. What is known, however, is that self-reported mental illness and overdose mortality among young people have generally increased more in Sweden than in most other European countries, Högberg explains.

The trend is described as worrying and it is believed that those who perform poorly at school run a “significantly higher risk of suffering from serious psychiatric conditions” than others in the future and that there is also an increased risk of suicide and addiction.

– Another way of putting it is that mental health inequalities have increased, and that this has been driven mainly by girls and young people with a Swedish background. However, the trends for students with a foreign background are difficult to interpret as the most common countries of origin of the students vary over the period, continues the associate professor.

“Extensive need for support”

The researchers argue that it is necessary to carefully analyze the actual impact of the various school reforms on the mental health of young people and work actively to reduce the number of school failures.

They emphasize that so far we can only say with certainty that there is a link between excess risk of mental health problems and poor school performance we cannot say how the different factors interact.

– At the moment, we can’t comment on the causal link, but we plan to look at it more closely in the future. Regardless, this is a very vulnerable group with extensive support needs, needs that unfortunately do not seem to be adequately met today, concludes Björn Högberg.

Birth control pills can double the risk of heart attack

Published 1 March 2025
– By Editorial Staff

Use of the contraceptive pill can double the risk of heart attack and stroke, according to a study from Nordsjællands Hospital in Denmark. However, the researchers emphasize that the absolute risk is low and remind that there are alternative contraceptives.

Previous research has shown that hormonal contraceptives with estrogen increase the risk of blood clots in the bones and lungs. However, the link between contraceptive pills and the risk of cardiovascular disease has been less studied.

The study, published in the BMJ, is based on data from 2.2 million Danish women between 1996 and 2021. The researchers analyzed who suffered from blood clots in the brain and heart and examined the association with contraceptive use.

The results show that the risk was highest for women who used the pill, the contraceptive ring or the contraceptive patch, which contain both estrogen and progestin. Progestin-only pill use also increased the risk, but to a lesser extent, by 50%.

– In figures, our study shows that if 100 000 women took the pill for a year, 21 more would develop blood clots in the brain and 10 more in the heart, compared to if they did not take the pill, lead researcher Amani Meaidi told Norwegian state broadcaster NRK.

Health care should take account

The researchers emphasize that the risk of heart attack and stroke before menopause is very low. Even if the risk doubles, it is still a rare side effect. At the same time, they believe that healthcare providers should take this into account when prescribing contraceptives.

Meanwhile, IUDs stood out in the study by showing no increased risk of heart attack or stroke. The researchers believe that this may be due to the low hormone content, but other factors may also play a role.

It is important that we as doctors and researchers continue to be curious about the side effects of hormonal contraceptives, so that we can help women choose the safest one, says Meaidi.

Previous studies have also shown that the pill can increase the risk of depression.

Mobile phone addiction fuels anxiety among young adults

Published 24 February 2025
– By Editorial Staff
Many young people experience destructive screen addiction.

Young people feel that they are becoming increasingly dependent on their cell phones. Young women, in particular, generally feel more stress related to their cell phones, according to a study from the University of Gothenburg.

The study, published in Nordicom Review, is based on a national survey on mobile phone use and focus group interviews with young adults aged 20 to 35. The results show that many experience a moral stress in relation to their mobile phone.

– We see that young people in Sweden largely feel that they do not use their smartphones in the way they would like. They feel dependent on their phone in a way that gives rise to negative feelings, says Professor André Jansson at the University of Gothenburg, who led the study, in a press release.

Young women experience more stress related to mobile phone use than young men. They often feel more dependent and experience less control over their use.

– They often feel that they waste time on their phones and that it affects their ability to focus on other, according to them, more important aspects of life, says Professor Karin Fast at the University of Gothenburg, who led the focus group study.

Difficulty with self-reflection

The study shows that people often see others as more vulnerable to the negative effects of cell phones than themselves.

– Distancing oneself from behaviors that are perceived as problematic is a well-known phenomenon in research. People want to see themselves as better than others at dealing with the negative effects of media, says Jansson and continues:

– At the same time, we see that young adults are generally more aware of the problems smartphones can cause, including for themselves, compared to older individuals.

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