Sunday, August 31, 2025

Polaris of Enlightenment

Ayahuasca study gives hope to the depressed

Published 9 July 2022
– By Editorial Staff
Ayahuasca vines in the Amazon rainforest.
3 minute read

A team of Brazilian researchers has performed the first randomized, placebo-controlled clinical trial on ayahuasca – a psychedelic drink made from plants from the Amazon. The results, published in the journal ‘Psychological Medicine’, suggest that ayahuasca may work against major depression.

Ayahuasca, a word derived from the indigenous language Quechua, means “vine of the spirits.” Indigenous peoples from the Amazon region of Brazil, Peru, Colombia and Ecuador have been using the drink for therapeutic and spiritual purposes for centuries, and probably much longer than that.

The medicinal drink consists of two plants. Banisteriopsis caapi, a vine that winds its way up treetops and across rivers, is boiled together with psychotria viridis, a shrub whose leaves contain the psychoactive molecule DMT. Since the early 1930s, it has been documented how Brazilian religions began to take shape around the use of ayahuasca as a sacrament. By the 1980s, ayahuasca rituals had spread to the rest of Brazil and to other parts of the world.

Ayahuasca did not become legal in Brazil for religious reasons until 1987, after the country’s federal medical authority recognized the fact that “religious group members” had experienced outstanding benefits from taking it. Some people who drank ayahuasca described it as finding peace with themselves.

In the study, conducted at the Federal University of Brazil in Rio Grande do Norte, researchers used 218 people with depression. 29 of them were selected because their depression could not be treated. No one had a history of psychotic disorders, such as schizophrenia – something that ayahuasca is reported to make worse.

The 29 people were randomly selected to receive a treatment session where they received either an ayahuasca drink or a placebo drink. The placebo drink was a brown drink that tasted bitter and sour, made from water, yeast, citric acid and caramel color. Zinc sulfate mimicked two well-known side effects of ayahuasca, namely nausea and vomiting.

The treatments were done in a hospital, but the room was designed as a quiet and comfortable living room. The strong effects of ayahuasca – which include dreamlike visions, vomiting and intense introspection – usually last for about 4 hours. During this period, participants listened to two different playlists, one with instrumental music and another with Portuguese songs.

The patients were supervised by two assistants who were there to support if anyone felt anxious during the intense, emotional psychic experience.

One day after treatment, a large improvement of 50 percent was observed in all patients, which included reduced anxiety and better mood. One week later, 64 percent of those who received ayahuasca felt that their depression had improved. 27 percent of the placebo group felt the same way.

The study supports previous research done in Brazil in 2015, where it was tested whether ayahuasca could work as an antidepressant drug. The study, which Dr. Jaime Hallak led at the University of São Paulo, also showed that as little as one session of ayahuasca had an antidepressant effect. All 17 participants reported that their depressive symptoms had decreased in the first hours after taking ayahuasca. The effect lasted 21 days. The study received a lot of attention from researchers, while the promising results were limited because there was no control group on placebo. Dr. Hallak and the other researchers at the University of São Paulo were involved also in this study.

In clinical trials on depression, up to 45 percent of patients taking placebo may report major benefits. The placebo effect of depression is so strong that some researchers have questioned whether antidepressant medication really works.

It should be added that the traditional view of ayahuasca emphasizes the importance of an experienced and knowledgeable supervisor needing to be present to support participants during a treatment session – what is popularly called a “shaman”. This is mainly in the light of the drink’s strong psychoactive properties and that the risk of serious side effects during careless use is otherwise stated to be significant.

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Memory problems increase among Nordic children

Published 27 August 2025
– By Editorial Staff
Memory-related medical visits have tripled in a short time among children aged 5-14 in Sweden.
2 minute read

More children and young people are seeking medical care for memory problems in both Sweden and Norway. The Swedish Radiation Protection Foundation believes the increase may be linked to radiation exposure, which has also increased during the same period.

In Norway, there has been an increase in recent years in the number of people seeking medical care for memory problems, not only among adults but also among children. Between 2019 and 2024, for example, the number of doctor visits related to memory problems more than doubled, from 41,722 doctor visits to 98,910 doctor visits in 2024. Among children aged 5-14, visits had nearly tripled.

I have never seen such a dramatic increase in these figures before, says Richard Aubrey White, researcher and statistician at the Norwegian Institute of Public Health (FHI), to Norwegian state broadcaster NRK.

In Sweden too, the number of doctor visits regarding memory problems has increased, both among children and adults. Memory problems, which can be classified as mild cognitive impairment, is a diagnosis found under diagnostic code R41. In 2011, 577 children were registered with diagnosis R41 as the primary diagnosis; by 2024, the number had increased to 5,975.

Microwave radiation

The Swedish Radiation Protection Foundation believes the increase may be due to increased exposure to microwave radiation among people, pointing out that repeated research has shown, for example, that radiation has a harmful effect on memory.

Repeated scientific studies have also shown that people exposed to elevated levels of this radiation have an increased occurrence of various symptoms, called microwave syndrome, where impaired memory is one of the most common symptoms“, writes the Swedish Radiation Protection Foundation.

Cell towers associated with worse memory

Even in case studies examining the health effects of 5G, impaired memory tends to be one of the most commonly reported effects. Reports of impaired memory, concentration difficulties, and headaches are also common when living near cell towers.

The Swedish Radiation Protection Foundation notes that radiation has increased dramatically during the same period as the increase in doctor visits for memory problems has occurred. At the same time, mobile phones have begun to be used more extensively by both children and adults during the same period.

The increased memory problems, both among children and adults, are thus an expected effect resulting from the increase in people’s exposure to microwave radiation”.

Colorectal cancer affects more young Swedes

Published 23 August 2025
– By Editorial Staff
The study also shows that mortality has increased among both younger and older patients for up to ten years after cancer diagnosis.
2 minute read

Colorectal cancer is increasing among young people in Sweden, according to research from the Karolinska Institute. Researchers suggest that lifestyle factors, such as sedentary behavior and obesity, may be the cause.

In the study, which was published in Annals of Oncology, researchers examined over 135,000 Swedish patients who had colorectal cancer between 1993 and 2019.

The results show that the number of younger people under 50 who develop this form of cancer has increased over the past three decades. For rectal cancer, the number of new cases among younger people has increased by 2.04 percent per year, and for left-sided and right-sided colon cancer, the increase is 2.41 and 2.64 percent per year respectively. Overall, the disease has become two to three times more common among younger people.

Detected later in younger patients

Younger patients also more often had metastatic cancer compared to older patients, suggesting they had lived with symptoms longer before the cancer was discovered. Researchers emphasize that it’s important for both the public and healthcare professionals to know that this type of cancer can also affect younger people. This is particularly important since the chance of curing cancer increases with early detection.

The study also shows that mortality has increased among both younger and older patients up to ten years after cancer diagnosis.

This is remarkable, since patients are often considered cured after such a long time. Our results challenge that view and underscore the need for more research into why this is happening, as well as long-term follow-up and support for both young and older patients, says Cecilia Radkiewicz, researcher at the Department of Molecular Medicine and Surgery at the Karolinska Institute in Stockholm.

Lifestyle may be the cause

It’s unclear what actually lies behind the increase in colorectal cancer among young people, but researchers believe it doesn’t appear to be driven by traditional risk factors such as inflammatory bowel disease or heredity. Instead, the results suggest that lifestyle factors may be decisive.

Childhood obesity, sedentary lifestyle, and antibiotic use have been highlighted as contributing factors, although the underlying biological mechanisms remain unclear, says Radkiewicz.

Just a few puffs are enough – how quickly vaping damages the lungs

Published 21 August 2025
– By Editorial Staff
Researchers have for the first time been able to demonstrate a direct link between inhaled nicotine from e-cigarettes and inflammatory markers in the blood.
2 minute read

Just a few puffs of an e-cigarette, or vape, containing nicotine can trigger inflammation in the lungs, according to research from Uppsala University in Sweden.

The researchers, who received funding from the Swedish Heart-Lung Foundation, tested 22 healthy individuals on two different occasions. The participants then smoked e-cigarettes both with and without nicotine for half an hour each.

When the researchers analyzed the blood samples, they found that participants exposed to nicotine-containing e-cigarettes showed elevated levels of inflammatory markers in their blood. According to the researchers, this could mean that just a few inhalations are enough to trigger an inflammatory reaction in lung tissue.

The results are alarming, as they clearly show that e-cigarettes with nicotine are not a harmless alternative to cigarettes. We have long worked to spread scientifically-based knowledge about nicotine’s health effects, and this research strengthens our conviction that tobacco and new nicotine products should be treated equally under the law, says Kristina Sparreljung, Secretary General of the Swedish Heart-Lung Foundation, in a press release.

For the first time, researchers have been able to demonstrate a direct link between inhaled nicotine and specific inflammation markers in the blood that are connected to the lungs. The researchers believe the absorption rate is particularly concerning, as the body absorbs nicotine faster than with nicotine patches, for example.

Our results are in line with previous studies where nicotine from e-cigarettes has been shown to affect blood vessels by increasing levels of vascular damage markers in the blood. It’s remarkable that even single occasions can produce biological effects. In the long term, this could contribute to the development of both lung diseases and cardiovascular disease, says Fariborz Mobarrez, lecturer and researcher at the Department of Medical Sciences at Uppsala University.

Obesity the most common risk factor for heart attack among Swedes

Published 20 August 2025
– By Editorial Staff
Women who suffer heart attacks often have more risk factors and a worse prognosis than men.
2 minute read

Obesity has overtaken smoking as the primary cause of heart attack among young adults in Sweden, a new study shows.

In the study, which was published in European Heart Journal – Quality of Care and Clinical Outcomes, researchers followed 44,254 people aged 18–59 after they suffered their first heart attack. The study is a registry-based study and was conducted with support from the Swedish Heart-Lung Foundation.

The results show that three out of four young adults who suffered a heart attack had at least one known risk factor – most commonly high blood pressure, diabetes, smoking, or obesity. Furthermore, the study shows that obesity has overtaken smoking as the most common risk factor in this age group. The reason is that the number of smokers has decreased, but at the same time the proportion suffering from obesity has increased markedly. For example, one in four suffered from obesity in 2006, and more than one in three in 2021.

It is concerning that the proportion of people with obesity has overtaken the proportion of smokers as the most common risk factor among young adults. But it also shows that we can do much to prevent heart attacks by finding and treating risk factors in time, says Moa Simonsson, researcher and senior physician in cardiology at Karolinska University Hospital in Stockholm, in a press release.

Difference between men and women

Men run a greater risk of suffering a heart attack compared to women and are often affected earlier in life. At the same time, the study shows that women who suffer heart attacks often have more risk factors, but also that they have a worse prognosis after a heart attack.

It seems that women who have a heart attack need to have a heavier burden of risk factors than men to be affected. This shows that we need to understand more about women’s particular risks, such as complications during pregnancy, says Simonsson.

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