Tuesday, March 18, 2025

Polaris of Enlightenment

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Australia approves psychedelics for medical use

Published 5 July 2023
– By Editorial Staff
Psilocybe semilanceata, or liberty cap, grows in many parts of the world, including northern Europe.

As of July 1, psychiatrists in Australia will be able to prescribe MDMA and psilocybin, which are found in psychedelic mushrooms. This makes Australia the first country to formally approve these drugs for medical treatment.

Both MDMA and psilocybin are classified as narcotics in Sweden and many other countries. Now, however, patients in Australia can be prescribed the substances as medicine for mental health problems, reports The Guardian. The country is the first in the world to approve the substances for clinical treatment.

Psilocybin is already formally legal in a few countries, including Brazil, Nepal and the Netherlands, but it is not used in medical or psychiatric settings. MDMA is currently under investigation for medical use in the United States, and is permitted for limited personal use in the province of British Columbia, Canada. Psychedelic substances, including psilocybin and MDMA, can exceptionally be distributed in Canada through a special application to the Ministry of Health. However, Australia will be the first country to allow the substances to be prescribed by doctors for treatment.

MDMA is primarily used to treat post-traumatic stress disorder (PTSD), while psilocybin is primarily used to treat depression.

Mixed views on the decision

Psychology professor Susan Rossell, who is currently conducting a major study in Australia on depression and psilocybin, is “cautious” about the new legislation, saying that the medical studies are not yet comprehensive enough.

– We’ve got no data on long-term outcomes at all, so that worries me a lot, says Rossel in a comment to The Guardian.

But Dr. Mike Musker, a mental health researcher at the University of South Australia, calls it a success and “one of the biggest evolutions in psychiatry in the last 70 years”.

The role of MDMA in psychiatry has also been discussed in Sweden, including at a 2019 conference on the topic organized by the Network on Psychedelic Science, which was attended by several of the world’s leading researchers in the field. A so-called phase 3 trial at the University of California, published in Nature Medicine in 2021, for the treatment of patients with severe PTSD, including war veterans, has also prompted Gita Rajan, a doctor and PhD student at Karolinska Institutet, to plan a pilot study in Sweden. This study will investigate the effects of MDMA on her patient population of people suffering from PTSD after severe sexual violence.

MDMA increases the possibilities for treatment more than any other drug available today, Rajan said in a commentary on the study to taxpayer-funded SVT.

The Facts: MDMA and Psilocybin

Psilocybin is a substance found in mushrooms of the genus psilocybin that induces so-called psychedelic states of consciousness. Thoughts, feelings, and perceptions are greatly altered in a way that is often described as a spiritual experience. The substance belongs to the class of enteogens, traditional natural medicines with hallucinogenic properties used in psychotherapeutic and shamanistic contexts. In recent years, it has received widespread attention in the West for its potential healing effects, with warnings that careless use is very risky and can cause both panic attacks and psychotic episodes.

MDMA (methylenedioxymethamphetamine) is a central stimulant introduced in the early 1900s and originally used as a weight-loss drug. It is the psychoactive substance in the party drug known as "ecstasy," although in practice it is often a mixture of several different substances. MDMA affects the nervous system and, like psilocybin, can induce psychedelic states of consciousness. It is classified as an empathogen, which affects the state of mind rather than perception. It releases serotonin in the brain, usually causing intense euphoria and alertness, but can also cause hyperactivity, anxiety, and decreased self-control. Like psilocybin, it has attracted attention for its potentially medicinal effects, while also warning that careless use is very dangerous. Among other things, it can cause neurotoxic damage with symptoms such as persistent anxiety, fatigue, difficulty sleeping, and depression.

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Mental health crisis deepens in Swedish schools

Welfare collapse

Published 7 March 2025
– By Editorial Staff

Mental health problems among young Swedes have skyrocketed in recent decades, with the worst performers being those who fail to meet school targets.

A comprehensive study shows that there are clear links between psychiatric diagnoses such as anxiety and depression and poor school performance.

Researchers at Umeå University have followed over three million students between 1990 and 2018 and conclude that the results show that “school performance and mental illness have become increasingly interlinked”.

Psychiatric diagnoses have increased across the youth population, but the trend has been most dramatic among low-achieving students. Mortality from suicide and substance abuse has also increased in this group, while it has remained stable for other youth”, the university writes.

– The increase applies both in the short and long term. We study students when they are in grade 9, but also follow them for several years after they leave primary school. The increase in ill-health is evident even into their 20s, explains Associate Professor Björn Högberg, who participated in the study.

It is seen that mental illness among young people has increased since the 1990s and that Swedish schools have undergone several reforms and changes during this period. These changes have led to an increasing number of students failing to enter or complete their upper secondary education.

Increased risk of suicide

By following all students who completed grade 9 in Sweden between 1990 and 2018, we can see how the correlation between school failure and psychiatric diagnoses has become stronger over time.

– As far as we know, no similar studies have been conducted in any other country, so we do not know if this trend is unique to Sweden. What is known, however, is that self-reported mental illness and overdose mortality among young people have generally increased more in Sweden than in most other European countries, Högberg explains.

The trend is described as worrying and it is believed that those who perform poorly at school run a “significantly higher risk of suffering from serious psychiatric conditions” than others in the future and that there is also an increased risk of suicide and addiction.

– Another way of putting it is that mental health inequalities have increased, and that this has been driven mainly by girls and young people with a Swedish background. However, the trends for students with a foreign background are difficult to interpret as the most common countries of origin of the students vary over the period, continues the associate professor.

“Extensive need for support”

The researchers argue that it is necessary to carefully analyze the actual impact of the various school reforms on the mental health of young people and work actively to reduce the number of school failures.

They emphasize that so far we can only say with certainty that there is a link between excess risk of mental health problems and poor school performance we cannot say how the different factors interact.

– At the moment, we can’t comment on the causal link, but we plan to look at it more closely in the future. Regardless, this is a very vulnerable group with extensive support needs, needs that unfortunately do not seem to be adequately met today, concludes Björn Högberg.

Birth control pills can double the risk of heart attack

Published 1 March 2025
– By Editorial Staff

Use of the contraceptive pill can double the risk of heart attack and stroke, according to a study from Nordsjællands Hospital in Denmark. However, the researchers emphasize that the absolute risk is low and remind that there are alternative contraceptives.

Previous research has shown that hormonal contraceptives with estrogen increase the risk of blood clots in the bones and lungs. However, the link between contraceptive pills and the risk of cardiovascular disease has been less studied.

The study, published in the BMJ, is based on data from 2.2 million Danish women between 1996 and 2021. The researchers analyzed who suffered from blood clots in the brain and heart and examined the association with contraceptive use.

The results show that the risk was highest for women who used the pill, the contraceptive ring or the contraceptive patch, which contain both estrogen and progestin. Progestin-only pill use also increased the risk, but to a lesser extent, by 50%.

– In figures, our study shows that if 100 000 women took the pill for a year, 21 more would develop blood clots in the brain and 10 more in the heart, compared to if they did not take the pill, lead researcher Amani Meaidi told Norwegian state broadcaster NRK.

Health care should take account

The researchers emphasize that the risk of heart attack and stroke before menopause is very low. Even if the risk doubles, it is still a rare side effect. At the same time, they believe that healthcare providers should take this into account when prescribing contraceptives.

Meanwhile, IUDs stood out in the study by showing no increased risk of heart attack or stroke. The researchers believe that this may be due to the low hormone content, but other factors may also play a role.

It is important that we as doctors and researchers continue to be curious about the side effects of hormonal contraceptives, so that we can help women choose the safest one, says Meaidi.

Previous studies have also shown that the pill can increase the risk of depression.

Mobile phone addiction fuels anxiety among young adults

Published 24 February 2025
– By Editorial Staff
Many young people experience destructive screen addiction.

Young people feel that they are becoming increasingly dependent on their cell phones. Young women, in particular, generally feel more stress related to their cell phones, according to a study from the University of Gothenburg.

The study, published in Nordicom Review, is based on a national survey on mobile phone use and focus group interviews with young adults aged 20 to 35. The results show that many experience a moral stress in relation to their mobile phone.

– We see that young people in Sweden largely feel that they do not use their smartphones in the way they would like. They feel dependent on their phone in a way that gives rise to negative feelings, says Professor André Jansson at the University of Gothenburg, who led the study, in a press release.

Young women experience more stress related to mobile phone use than young men. They often feel more dependent and experience less control over their use.

– They often feel that they waste time on their phones and that it affects their ability to focus on other, according to them, more important aspects of life, says Professor Karin Fast at the University of Gothenburg, who led the focus group study.

Difficulty with self-reflection

The study shows that people often see others as more vulnerable to the negative effects of cell phones than themselves.

– Distancing oneself from behaviors that are perceived as problematic is a well-known phenomenon in research. People want to see themselves as better than others at dealing with the negative effects of media, says Jansson and continues:

– At the same time, we see that young adults are generally more aware of the problems smartphones can cause, including for themselves, compared to older individuals.

Over the counter eye drops consist of 100 percent PFAS

Published 19 February 2025
– By Editorial Staff
Daily use of the drops produces about 120 milligrams of PFAS in the eyes.

Evo Tears brand eye drops are 100% PFAS but are sold over-the-counter in Swedish pharmacies and opticians.

PFASs are a large and complex group of chemicals with over 10,000 identified substances. They are used in everything from plastic products and clothing to beauty products and frying pans. Because they are difficult to break down, they are often referred to as perpetual chemicals.

Evo Tears is marketed as a lubricating and soothing treatment for dry eyes. However, it is less clear that they contain only one ingredient – PFAS.

Daily use of the drops in the eyes produces about 120 milligrams of PFAS. This is over two million times more than the maximum tolerable intake limit via food and water.

– I would probably not use these drops myself, says chemistry professor Tuulia Hyötyläinen to Dagens ETC, which was the first to report on the eye drops.

Harmful substances

Some PFAS contain harmful substances that can negatively affect both humans and the environment. High levels have been linked to reduced fertility, high blood pressure and obesity. Studies have also shown links to poorer gross motor development in infants and ADHD in girls exposed through breast milk. Norwegian scientists warned last year that children in Norway have excessive levels of these chemicals in their bodies.

The so-called “PFAS scandal” in Kallinge attracted a lot of attention after residents ingested large amounts of the chemicals through the drinking water. For several decades, the Swedish Armed Forces had used firefighting foam containing PFAS, which leaked into the groundwater. The victims sued the municipally owned company Ronneby Miljöteknik, and after a long legal process, the Supreme Court finally awarded damages.

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