Saturday, April 19, 2025

Polaris of Enlightenment

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Australia approves psychedelics for medical use

Published 5 July 2023
– By Editorial Staff
Psilocybe semilanceata, or liberty cap, grows in many parts of the world, including northern Europe.

As of July 1, psychiatrists in Australia will be able to prescribe MDMA and psilocybin, which are found in psychedelic mushrooms. This makes Australia the first country to formally approve these drugs for medical treatment.

Both MDMA and psilocybin are classified as narcotics in Sweden and many other countries. Now, however, patients in Australia can be prescribed the substances as medicine for mental health problems, reports The Guardian. The country is the first in the world to approve the substances for clinical treatment.

Psilocybin is already formally legal in a few countries, including Brazil, Nepal and the Netherlands, but it is not used in medical or psychiatric settings. MDMA is currently under investigation for medical use in the United States, and is permitted for limited personal use in the province of British Columbia, Canada. Psychedelic substances, including psilocybin and MDMA, can exceptionally be distributed in Canada through a special application to the Ministry of Health. However, Australia will be the first country to allow the substances to be prescribed by doctors for treatment.

MDMA is primarily used to treat post-traumatic stress disorder (PTSD), while psilocybin is primarily used to treat depression.

Mixed views on the decision

Psychology professor Susan Rossell, who is currently conducting a major study in Australia on depression and psilocybin, is “cautious” about the new legislation, saying that the medical studies are not yet comprehensive enough.

– We’ve got no data on long-term outcomes at all, so that worries me a lot, says Rossel in a comment to The Guardian.

But Dr. Mike Musker, a mental health researcher at the University of South Australia, calls it a success and “one of the biggest evolutions in psychiatry in the last 70 years”.

The role of MDMA in psychiatry has also been discussed in Sweden, including at a 2019 conference on the topic organized by the Network on Psychedelic Science, which was attended by several of the world’s leading researchers in the field. A so-called phase 3 trial at the University of California, published in Nature Medicine in 2021, for the treatment of patients with severe PTSD, including war veterans, has also prompted Gita Rajan, a doctor and PhD student at Karolinska Institutet, to plan a pilot study in Sweden. This study will investigate the effects of MDMA on her patient population of people suffering from PTSD after severe sexual violence.

MDMA increases the possibilities for treatment more than any other drug available today, Rajan said in a commentary on the study to taxpayer-funded SVT.

The Facts: MDMA and Psilocybin

Psilocybin is a substance found in mushrooms of the genus psilocybin that induces so-called psychedelic states of consciousness. Thoughts, feelings, and perceptions are greatly altered in a way that is often described as a spiritual experience. The substance belongs to the class of enteogens, traditional natural medicines with hallucinogenic properties used in psychotherapeutic and shamanistic contexts. In recent years, it has received widespread attention in the West for its potential healing effects, with warnings that careless use is very risky and can cause both panic attacks and psychotic episodes.

MDMA (methylenedioxymethamphetamine) is a central stimulant introduced in the early 1900s and originally used as a weight-loss drug. It is the psychoactive substance in the party drug known as "ecstasy," although in practice it is often a mixture of several different substances. MDMA affects the nervous system and, like psilocybin, can induce psychedelic states of consciousness. It is classified as an empathogen, which affects the state of mind rather than perception. It releases serotonin in the brain, usually causing intense euphoria and alertness, but can also cause hyperactivity, anxiety, and decreased self-control. Like psilocybin, it has attracted attention for its potentially medicinal effects, while also warning that careless use is very dangerous. Among other things, it can cause neurotoxic damage with symptoms such as persistent anxiety, fatigue, difficulty sleeping, and depression.

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Iron deficiency common among Swedish high school girls

Published 6 April 2025
– By Editorial Staff
Iron deficiency can cause concentration difficulties.

More than one in three Swedish female high school students has an iron deficiency, according to a study from Lund University. The risk was found to be particularly high among vegetarians and vegans.

The study, published in the European Journal of Nutrition, involved 475 upper secondary school students from two schools in Malmö and Lund. Participants answered questions about dietary habits and menstruation, among other things, and then provided blood samples.

The blood samples were analyzed with a focus on iron status, which was then compared to the participants’ diet. The results showed that 38% of high school girls were iron deficient. Among vegetarians and vegans, the percentage was close to 70%, compared to 30% among meat eaters. Even pescatarians – who exclude red meat and chicken – had a higher prevalence of iron deficiency.

It is positive that many young people are choosing a more plant-based diet, which reduces the risk of various chronic diseases such as cancer and cardiovascular disease and is also good for the environment. But you need to think about how you get iron. We hope that the results draw attention to the importance of replacing meat with iron-rich foods, says Anna Stubbendorff, dietician and PhD student in nutritional epidemiology at Lund University, in a press release.

Iron deficiency can cause fatigue, difficulty concentrating and in severe cases anemia. The body’s ability to absorb iron is affected by what else you eat, whether the iron comes from meat or plant sources.

It’s important to eat plenty of whole grains and legumes such as beans, peas, and lentils. Vitamin C and acids – for example, sauerkraut, kimchi, or sourdough bread – consumed at the same time as the meal increase iron absorption. Coffee and tea reduce absorption. We also saw that those who reported eating more fruit had a lower incidence of iron deficiency.

The researchers now want to develop a screening method that can help school health services identify high school girls at risk of iron deficiency.

Omega-3 found to slow down biological aging

Published 31 March 2025
– By Editorial Staff

Omega-3 can clearly slow down biological aging in all age groups, according to a new study. The effect was even greater when combined with strength training and vitamin D.

The study, which was conducted by researchers at the University of Zurich, the Hospital University of Toulouse and Harvard University, among others, examined the effect of vitamin D, omega-3 and exercise on biological ageing.

In total, the DO-HEALTH study involved 2,157 participants from several European countries. The aim of the long-term study is to prevent healthy ageing and to study the effects of omega-3 and vitamin D.

Participants were divided into different groups, with some receiving vitamin D or omega-3 daily, while others received a placebo. In addition, strength training (30 minutes, three times a week) was compared with joint mobility training of the same duration.

By varying the combinations, the researchers were able to analyze both individual and combined effects, for example in those who received both vitamin D and omega-3.

The analysis, published in Nature Aging, shows that a daily intake of one gram of omega-3 for three years was able to slow biological aging by almost three months compared to those who did not take the supplement.

Effect the same regardless of age

In the group that combined omega-3, vitamin D and strength training, the effect was even greater, slowing down aging by almost four months. The combination also reduced the risk of invasive cancer by 61% and the risk of early osteoporosis by 39%.

The effect on biological ageing was the same regardless of gender, age or BMI.

Omega-3 fatty acids are mostly found in oily fish and are important for building and repairing cells, among other things. They can also affect blood pressure regulation, kidney function and the immune system.

In the next step, the researchers plan to include more participants to get a broader sample and study how different lifestyles affect the results.

Sweden to abolish burnout diagnosis under new WHO guidelines

Published 19 March 2025
– By Editorial Staff
The diagnostic criteria have long been criticized for being too broad and vague, leaving much room for interpretation by individual doctors.

Fatigue syndrome will be removed as a diagnosis by 2028, following new guidelines from the World Health Organization (WHO).

Sweden is currently the only country that has fatigue syndrome, also known as burnout, as a recognized diagnosis. The number of stress-related sick leaves is increasing and every year around 20,000 Swedes are taken ill with the diagnosis.

However, as of 2028, the diagnosis will disappear completely from Sweden, reports Psykologitidningen. The background to the decision is that the World Health Organization (WHO) is updating the international diagnosis system and no longer wants to see national diagnoses. In other words, it is not the National Board of Health and Welfare’s decision, but the new guidelines that form the basis for the removal.

Psychologist Elin Lindsäter, one of Sweden’s leading researchers in the field, basically welcomes the change and believes it can benefit patients, as the diagnosis has been broad and vague and used in different ways around the country. At the same time, she worries that the resulting void could lead to rapid decisions and differences between regions. Lindsäter has been in contact with the Minister for Social Affairs, Jakob Forssmed, where she has pointed out the need for national coordination.

– A government commission to investigate the situation seems to be underway, she told the paper.

“Can only get better”

At the same time, she understands that the change may cause concern among patients, who have already pointed out that it can be difficult to get the right care.

– This change puts the clinical picture on the table and forces us to act and think differently. I assume that things can only get better, but initially there may be legitimate concerns for many, with a risk of falling through the cracks.

Magdalena Fresk, Head of the Classifications and Terminology Unit at the National Board of Health and Welfare, says that the previous diagnosis system was many years old and that this is “a long-awaited, medically updated version”. This year they will be working on the translation for the new WHO guidelines.

We have a number of issues that we know we will need to work on to ensure that there are no problems for patients and that it works as well as possible in the future, she told the Bonnier newspaper DN.

Mental health crisis deepens in Swedish schools

Welfare collapse

Published 7 March 2025
– By Editorial Staff

Mental health problems among young Swedes have skyrocketed in recent decades, with the worst performers being those who fail to meet school targets.

A comprehensive study shows that there are clear links between psychiatric diagnoses such as anxiety and depression and poor school performance.

Researchers at Umeå University have followed over three million students between 1990 and 2018 and conclude that the results show that “school performance and mental illness have become increasingly interlinked”.

Psychiatric diagnoses have increased across the youth population, but the trend has been most dramatic among low-achieving students. Mortality from suicide and substance abuse has also increased in this group, while it has remained stable for other youth”, the university writes.

– The increase applies both in the short and long term. We study students when they are in grade 9, but also follow them for several years after they leave primary school. The increase in ill-health is evident even into their 20s, explains Associate Professor Björn Högberg, who participated in the study.

It is seen that mental illness among young people has increased since the 1990s and that Swedish schools have undergone several reforms and changes during this period. These changes have led to an increasing number of students failing to enter or complete their upper secondary education.

Increased risk of suicide

By following all students who completed grade 9 in Sweden between 1990 and 2018, we can see how the correlation between school failure and psychiatric diagnoses has become stronger over time.

– As far as we know, no similar studies have been conducted in any other country, so we do not know if this trend is unique to Sweden. What is known, however, is that self-reported mental illness and overdose mortality among young people have generally increased more in Sweden than in most other European countries, Högberg explains.

The trend is described as worrying and it is believed that those who perform poorly at school run a “significantly higher risk of suffering from serious psychiatric conditions” than others in the future and that there is also an increased risk of suicide and addiction.

– Another way of putting it is that mental health inequalities have increased, and that this has been driven mainly by girls and young people with a Swedish background. However, the trends for students with a foreign background are difficult to interpret as the most common countries of origin of the students vary over the period, continues the associate professor.

“Extensive need for support”

The researchers argue that it is necessary to carefully analyze the actual impact of the various school reforms on the mental health of young people and work actively to reduce the number of school failures.

They emphasize that so far we can only say with certainty that there is a link between excess risk of mental health problems and poor school performance we cannot say how the different factors interact.

– At the moment, we can’t comment on the causal link, but we plan to look at it more closely in the future. Regardless, this is a very vulnerable group with extensive support needs, needs that unfortunately do not seem to be adequately met today, concludes Björn Högberg.

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