Tuesday, April 22, 2025

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Broccoli may reduce the risk of stroke

Published 4 April 2024
– By Editorial Staff
Broccoli may also lower blood sugar and reduce the risk of cancer, according to previous studies.

Broccoli may contain compounds that both prevent and treat stroke, according to Australian research. Scientists believe a new treatment could be available within five years.

Stroke is often caused by the formation of a harmful blood clot in the brain, also known as acute ischemic stroke. The treatment commonly used for this type of stroke is a type of clot-busting drug (r-tPA), which is also designed to help slow the progression of brain damage.

– Unfortunately it is only successful in 20 per cent of cases, Dr. Xuyu (Johnny) Liu of the Heart Research Institute (HRI) in Australia said in a press release.

In the preclinical study, researchers spent three years looking at 23 different compounds found naturally in plants to see which ones would bind to the human compounds. And the compound that was found to work was sulforaphane.

– We are very excited at having isolated a natural compound that may have huge beneficial effects. Our studies will keep exploring how highly purified compounds from vegetables may have beneficial effects in disease processes, says Dr. Liu.

Stroke prevention?

Sulforaphane was able to partially prevent platelets from clumping together. It also prevented blood clots from forming under conditions similar to those found in our arteries. In experiments on mice, the researchers combined sulforaphane with r-tPA, the clot-busting drug, and found that the success rate was up to 60% higher than without the broccoli compound.

– Excitingly, this naturally occurring compound does not cause any signs of bleeding, which is a common side effect associated with blood-thinning agents tested in stroke treatment, says the researcher.

There is also evidence that the broccoli compound could prevent strokes, and Dr. Liu believes it could be used in the future.

– This means we could see paramedics treating ischaemic stroke patients with a broccoli-based medication as well as tPA on the way to hospital, he says.

Nature’s gifts

Broccoli is already known to be rich in vitamins, minerals and antioxidants. Previous studies have also shown that the vegetable, specifically the compound sulforaphane, can lower blood sugar and reduce the risk of cancer. The carotenoids found in broccoli are also thought to reduce the risk of heart disease and boost the immune system.

As sulforaphane moves into clinical trials, it is believed that a new preventive and anticoagulant treatment for stroke could be available in as little as five years.

– We want to understand how nature is giving us gifts to improve our health, says Dr. Liu.

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Iron deficiency common among Swedish high school girls

Published 6 April 2025
– By Editorial Staff
Iron deficiency can cause concentration difficulties.

More than one in three Swedish female high school students has an iron deficiency, according to a study from Lund University. The risk was found to be particularly high among vegetarians and vegans.

The study, published in the European Journal of Nutrition, involved 475 upper secondary school students from two schools in Malmö and Lund. Participants answered questions about dietary habits and menstruation, among other things, and then provided blood samples.

The blood samples were analyzed with a focus on iron status, which was then compared to the participants’ diet. The results showed that 38% of high school girls were iron deficient. Among vegetarians and vegans, the percentage was close to 70%, compared to 30% among meat eaters. Even pescatarians – who exclude red meat and chicken – had a higher prevalence of iron deficiency.

It is positive that many young people are choosing a more plant-based diet, which reduces the risk of various chronic diseases such as cancer and cardiovascular disease and is also good for the environment. But you need to think about how you get iron. We hope that the results draw attention to the importance of replacing meat with iron-rich foods, says Anna Stubbendorff, dietician and PhD student in nutritional epidemiology at Lund University, in a press release.

Iron deficiency can cause fatigue, difficulty concentrating and in severe cases anemia. The body’s ability to absorb iron is affected by what else you eat, whether the iron comes from meat or plant sources.

It’s important to eat plenty of whole grains and legumes such as beans, peas, and lentils. Vitamin C and acids – for example, sauerkraut, kimchi, or sourdough bread – consumed at the same time as the meal increase iron absorption. Coffee and tea reduce absorption. We also saw that those who reported eating more fruit had a lower incidence of iron deficiency.

The researchers now want to develop a screening method that can help school health services identify high school girls at risk of iron deficiency.

Omega-3 found to slow down biological aging

Published 31 March 2025
– By Editorial Staff

Omega-3 can clearly slow down biological aging in all age groups, according to a new study. The effect was even greater when combined with strength training and vitamin D.

The study, which was conducted by researchers at the University of Zurich, the Hospital University of Toulouse and Harvard University, among others, examined the effect of vitamin D, omega-3 and exercise on biological ageing.

In total, the DO-HEALTH study involved 2,157 participants from several European countries. The aim of the long-term study is to prevent healthy ageing and to study the effects of omega-3 and vitamin D.

Participants were divided into different groups, with some receiving vitamin D or omega-3 daily, while others received a placebo. In addition, strength training (30 minutes, three times a week) was compared with joint mobility training of the same duration.

By varying the combinations, the researchers were able to analyze both individual and combined effects, for example in those who received both vitamin D and omega-3.

The analysis, published in Nature Aging, shows that a daily intake of one gram of omega-3 for three years was able to slow biological aging by almost three months compared to those who did not take the supplement.

Effect the same regardless of age

In the group that combined omega-3, vitamin D and strength training, the effect was even greater, slowing down aging by almost four months. The combination also reduced the risk of invasive cancer by 61% and the risk of early osteoporosis by 39%.

The effect on biological ageing was the same regardless of gender, age or BMI.

Omega-3 fatty acids are mostly found in oily fish and are important for building and repairing cells, among other things. They can also affect blood pressure regulation, kidney function and the immune system.

In the next step, the researchers plan to include more participants to get a broader sample and study how different lifestyles affect the results.

Sweden to abolish burnout diagnosis under new WHO guidelines

Published 19 March 2025
– By Editorial Staff
The diagnostic criteria have long been criticized for being too broad and vague, leaving much room for interpretation by individual doctors.

Fatigue syndrome will be removed as a diagnosis by 2028, following new guidelines from the World Health Organization (WHO).

Sweden is currently the only country that has fatigue syndrome, also known as burnout, as a recognized diagnosis. The number of stress-related sick leaves is increasing and every year around 20,000 Swedes are taken ill with the diagnosis.

However, as of 2028, the diagnosis will disappear completely from Sweden, reports Psykologitidningen. The background to the decision is that the World Health Organization (WHO) is updating the international diagnosis system and no longer wants to see national diagnoses. In other words, it is not the National Board of Health and Welfare’s decision, but the new guidelines that form the basis for the removal.

Psychologist Elin Lindsäter, one of Sweden’s leading researchers in the field, basically welcomes the change and believes it can benefit patients, as the diagnosis has been broad and vague and used in different ways around the country. At the same time, she worries that the resulting void could lead to rapid decisions and differences between regions. Lindsäter has been in contact with the Minister for Social Affairs, Jakob Forssmed, where she has pointed out the need for national coordination.

– A government commission to investigate the situation seems to be underway, she told the paper.

“Can only get better”

At the same time, she understands that the change may cause concern among patients, who have already pointed out that it can be difficult to get the right care.

– This change puts the clinical picture on the table and forces us to act and think differently. I assume that things can only get better, but initially there may be legitimate concerns for many, with a risk of falling through the cracks.

Magdalena Fresk, Head of the Classifications and Terminology Unit at the National Board of Health and Welfare, says that the previous diagnosis system was many years old and that this is “a long-awaited, medically updated version”. This year they will be working on the translation for the new WHO guidelines.

We have a number of issues that we know we will need to work on to ensure that there are no problems for patients and that it works as well as possible in the future, she told the Bonnier newspaper DN.

Mental health crisis deepens in Swedish schools

Welfare collapse

Published 7 March 2025
– By Editorial Staff

Mental health problems among young Swedes have skyrocketed in recent decades, with the worst performers being those who fail to meet school targets.

A comprehensive study shows that there are clear links between psychiatric diagnoses such as anxiety and depression and poor school performance.

Researchers at Umeå University have followed over three million students between 1990 and 2018 and conclude that the results show that “school performance and mental illness have become increasingly interlinked”.

Psychiatric diagnoses have increased across the youth population, but the trend has been most dramatic among low-achieving students. Mortality from suicide and substance abuse has also increased in this group, while it has remained stable for other youth”, the university writes.

– The increase applies both in the short and long term. We study students when they are in grade 9, but also follow them for several years after they leave primary school. The increase in ill-health is evident even into their 20s, explains Associate Professor Björn Högberg, who participated in the study.

It is seen that mental illness among young people has increased since the 1990s and that Swedish schools have undergone several reforms and changes during this period. These changes have led to an increasing number of students failing to enter or complete their upper secondary education.

Increased risk of suicide

By following all students who completed grade 9 in Sweden between 1990 and 2018, we can see how the correlation between school failure and psychiatric diagnoses has become stronger over time.

– As far as we know, no similar studies have been conducted in any other country, so we do not know if this trend is unique to Sweden. What is known, however, is that self-reported mental illness and overdose mortality among young people have generally increased more in Sweden than in most other European countries, Högberg explains.

The trend is described as worrying and it is believed that those who perform poorly at school run a “significantly higher risk of suffering from serious psychiatric conditions” than others in the future and that there is also an increased risk of suicide and addiction.

– Another way of putting it is that mental health inequalities have increased, and that this has been driven mainly by girls and young people with a Swedish background. However, the trends for students with a foreign background are difficult to interpret as the most common countries of origin of the students vary over the period, continues the associate professor.

“Extensive need for support”

The researchers argue that it is necessary to carefully analyze the actual impact of the various school reforms on the mental health of young people and work actively to reduce the number of school failures.

They emphasize that so far we can only say with certainty that there is a link between excess risk of mental health problems and poor school performance we cannot say how the different factors interact.

– At the moment, we can’t comment on the causal link, but we plan to look at it more closely in the future. Regardless, this is a very vulnerable group with extensive support needs, needs that unfortunately do not seem to be adequately met today, concludes Björn Högberg.

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